Buy Colcrys (Colchicine) Online
Antidepressants cause agranulocytosis much less frequently. There is evidence of the development of a similar complication with the use of amitriptyline and imizine. Mianserin causes agranulocytosis in elderly people (mean age 67 years), and lithium carbonate - mainly in young and middle-aged men.
Back in the 80s of the last century, transient leukopenia was found in 10% of patients taking carbamazepine. Cases of severe granulocytopenia and agranulocytosis when taking carbamazepine are described mainly in elderly patients. Therefore, many experts advise with great care to prescribe this drug to patients over 60 years of age. The human body is inhabited by many microorganisms that coexist peacefully with it, and even quite often enter into symbiosis (they perform one or another positive function - they produce vitamin K in the intestines, prevent the growth of pathogenic bacteria, etc.).
Leukocytes, mainly granulocytes, have a inhibitory effect on the microflora and do not allow it to multiply excessively. With the development of agranulocytosis, uncontrolled multiplication of these microorganisms occurs, which leads to the development of infectious complications.
This place to buy colchicine for sale
Colchicine 0.6mg Online
Clinically, this is manifested by bloating and severe cramping abdominal pain, vomiting and diarrhea, sometimes with blood. With deep necrotic lesions of the alimentary tract, severe bleeding occurs that threatens the patient's life. In severe cases, jaundice may develop due to liver infection. Perforation of the resulting ulcers with the development of an acute abdomen clinic is rare.
Often, with agranulocytosis, pneumonia occurs, which takes on an atypical course with a tendency to form large abscesses (abscesses), the development of gangrene and the spread of the process to neighboring organs.
Damage to the lungs is manifested by coughing, shortness of breath, and when colchicine passes to the pleura, pain in the chest during breathing. In severe cases, the development of acute respiratory failure is possible.
Much less often with agranulocytosis, the infectious process begins from the bottom, covering the genitourinary organs (urethra, bladder, uterus and vagina in women). In this case, patients complain of pain and pain during urination, urinary retention, pain in the lower abdomen.
As a result of intoxication, arterial and venous hypotension develop, and functional murmurs are heard during auscultation of the heart. On the part of the kidneys, albuminuria (excretion of protein in the urine) is noted, associated with a reaction to infectious processes. In cases where the infectious process in the urinary system spreads to the kidneys, blood, protein, and epithelial cells of the renal tubules are determined in the urine.
Symptoms of septic complications in agranulocytosis. Since the body's defenses are reduced, with pronounced agranulocytosis, colchicine is generalized with the development of septic complications (the infection enters the blood, which is normally sterile, and spreads it throughout the body with the formation of purulent foci in various organs and tissues).
This pathology is extremely difficult, with high hyperthermia (41-42 degrees), severe intoxication and rapid dispersal of the infection throughout the body.
Especially characteristic is the appearance of lesions on the skin, which are black rashes that increase in size in ten to fifteen minutes. The same foci occur in the lungs, liver, kidneys and other organs.
About us
The course and prognosis of acute and chronic agranulocytosis.
Our core values:
- Be kind, for everyone you meet is fighting a hard battle
- Take on challenges
- Be honorable